Intrahepatic cholestasis of pregnancy (obstetric cholestasis)

This is a liver disorder that can develop in pregnancy, usually after 30 weeks gestation, but which sometimes develop as early as 8 weeks, affecting up to one in every 140 pregnant women. Symptoms can include:

• itching, usually on the hands and feet but which can be anywhere on the body
• dark urine, pale stools
• yellowing of the skin and whites of the eyes.